Prednisone isn’t always the best fit for everyone, especially if side effects get in the way. In 2025, you’ve got more choices than ever—meds that work differently and can sometimes mean fewer headaches (literally and figuratively). This article breaks down eight alternatives, giving honest pros, cons, and what you’ll want to ask your doctor. No stuffy jargon, just practical facts to help you partner in your care. Find out what’s new, what works, and what you should know before making a change.

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